The researchers compared two markers: the prostate-specific antigen (PSA) used to part inflammation levels in prostate disease, following this clinical attachment level (CAL) of the gums as a consequence teeth, which can be an symbol for periodontitis.
A PSA elevation of 4.0 ng/ml in the blood can be a sign of inflammation or malignancy. Patients with healthy prostate glands have decrease than 4.0ng/ml levels. A CAL estimate greater than 2.7 mm indicates periodontitis.
Like prostatitis, periodontitis also produces high inflammation levels.
"Subjects with both high CAL levels then moderate to severe prostatitis have higher levels of PSA or inflammation," stated Nabil Bissada, chair of the division of periodontics in the dental school.
Bissada added that this might explain why PSA levels can be high in prostatitis, but sometimes cannot be explained by what is event in the prostate glands.
"It is something outside the prostate gland that is causing an inflammatory reaction," he said.
Because periodontitis has been linked to heart disease, diabetes moreover rheumatoid arthritis, the researchers felt a link might exist to prostate disease.
Thirty-five men from a instance of 150 patients qualified for the study, funded by the branch of periodontology at the dental school. The participants were selected from patients at the University Hospitals Case Medical Center with mild to severe prostatitis, who had undergone nag biopsies and were found to have inflammation also in some patients, malignancies.
The participants were divided into two groups: those with high PSA levels for moderate or severe prostatitis or a malignancy and the certain with PSA levels below 4 ng/ml. All had not had dental work done for at least triple months as a result were given an examination to survey the gum health.
Looking at the results, the researchers from the dental school also the group of urology as a consequence the Institute of Pathology at the hospital found those with the most severe form of the prostatitis also showed signs for periodontitis.
Other authors on the paper, "Association in the middle of Periodontal Disease and Prostate-Specific Antigen Levels in Chronic Prostatitis Patients," were: Nishant Joshi, Sena Narendran, Rick Jurevic as a consequence Robert Skillicorn from the CWRU dental school; moreover Donald Bodner as a result Gregory T. MacLennon from the University Hospitals Case Medical Center.
From : Susan Griffith
Case Western Reserve University
